Hyaluronic Acid

Hyaluronic acid is one of the skin’s most essential structural molecules. It is a naturally occurring polysaccharide found in the dermis and epidermis, where it acts as the primary water-binding agent in the extracellular matrix. It is responsible for maintaining skin hydration, volume, and suppleness, and is one of the most extensively studied actives in both dermatology and aesthetic medicine.

Hyaluronic acid: the key to supple and plump skin

Young skin contains high concentrations of hyaluronic acid — but these levels decline significantly with age, UV exposure, and environmental stress. This progressive loss directly impacts skin density, elasticity, and barrier integrity, creating the characteristic dryness, fine lines, and loss of plumpness associated with skin aging. By the time visible signs appear, the skin’s HA reserves have already been substantially depleted.

Topical replenishment — through a formula that genuinely reaches the skin layers where it is needed — is the most direct way to restore and maintain adequate hydration levels.

Different molecular weights for different purposes

Not all hyaluronic acid acts the same way. Molecular weight determines where in the skin each fraction can penetrate and act. High molecular weight HA forms a protective film on the skin’s surface, reducing water loss and providing immediate plumping. Low molecular weight HA penetrates into deeper layers, delivering hydration where structural support is most needed. Very low molecular weight fragments interact directly with skin cells, supporting regeneration and barrier repair.

ALPHASCIENCE formulates with multiple molecular weights of hyaluronic acid to address hydration at every level of the skin simultaneously - from surface comfort to deep structural support. 

Skin benefits

Hyaluronic acid is one of the most versatile and universally beneficial actives in skincare, delivering immediate visible comfort while supporting the skin’s long-term structural integrity.

• Provides immediate and lasting deep hydration
• Visibly plumps fine lines
  
• Strengthens the skin barrier function, reducing transepidermal water loss and improving resilience
• Supports skin repair and regeneration, making it particularly valuable after aesthetic procedures

ALPHASCIENCE formulas containing Hyaluronic Acid
HA BOOSTER SERUM, ALPHA NIGHT PEEL SERUM, EYE MATRIX, SURFACE [CR], ULTRA FIRM, REGEN [Hx]