Stabilized Cysteamine simultaneously inhibits tyrosinase and peroxidase enzymes, interrupts melanin polymerization and acts as a potent free radical scavenger, targeting pigmentation at a deeper molecular level than most available actives. L-Ascorbic Acid provides complementary tyrosinase inhibition and protects against the UV-induced oxidative stress that drives melanogenesis. Acetyl-Glycyl-β-Alanine completes the formula by blocking melanin transfer to keratinocytes.
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MELA BRIGHT [C+] SERUM
30ml / 1 Fl Oz
Melasma and stubborn dark spot correcting antioxidant serum
A precision-formulated, hydroquinone-free serum clinically designed to address stubborn hyperpigmentation and melasma. Powered by our patented 3% Cysteamine complex highly stable and biocompatible working in synergy with melanin-regulating antioxidants to simultaneously target multiple pigmentation pathways for visible, lasting correction.
SKIN BENEFITS
- Intensive melasma and hyperpigmentation correction
- Targets multiple melanin production pathways simultaneously
- Leave-on formula — no rinsing required
- Suitable for all skin tones including phototypes V and VI
IDEAL FOR
- All skin types and phototypes
- Melasma and stubborn hyperpigmentation
- Post-inflammatory hyperpigmentation
- Suitable for phototypes V and VI
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![MELA BRIGHT [C+] SERUM](http://www.alphascience.com/cdn/shop/files/13_057b9aef-86b9-4ecf-bc85-c70591736aa6.png?v=1780341467&width=600)
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The Science Behind the Formula
Thanks to our exclusive NextGen Technology, Vitamin C and antioxidants remain stable, ensuring optimal efficacy and bioavailability - right up to the last drop.
Key ingredients
3% Stabilized Cysteamine
Cysteamine
Melanogenesis Inhibitor - Melasma -Correcting - Antioxidant
Learn more
Acetyl-Glycyl-β-Alanine
Acetyl-Glycyl-β-Alanine
Melanogenesis Inhibitor - Dark Spot Correcting - Brightening
Essential fraction of Gingko Biloba
Gingko Biloba
Barrier function strengthening - Microcirculation support - Radiance enhancing
Learn moreHOW TO USE
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1.
Apply 3–4 drops to clean, dry skin on the face, neck, and décolleté.
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2.
Gently massage until fully absorbed, avoid the eye contour area.
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3.
Follow with HA Booster serum for boosted hydration and/or a moisturizer adapted to your needs.
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4.
If exposed to sunlight, finish with Ultra Shield SPF 50 to protect your skin and maintain its radiance.
Safety Information:
Avoid direct contact with eyes; if contact occurs, rinse thoroughly with clean water. If irritation develops, reduce usage until the skin adjusts. Store in a cool, dark place. For external use only.
Efficacy of MELA BRIGHT [C+] versus Hydroquinone 4%
Frequently Asked Questions
MELA BRIGHT (C+) SERUM
Yes. Unlike hydroquinone, which is typically prescribed in cycles due to concerns around long-term use, cysteamine does not carry the same systemic or cytotoxic risks. It works by modulating melanin synthesis pathways without destroying melanocytes. Clinical evidence supports continuous daily use with an excellent safety and tolerance profile. No treatment breaks are required, though periodic reassessment with your practitioner is recommended.
In a clinical study conducted in Japan, Mela Bright [C+] was evaluated as being as effective as hydroquinone 4%, with up to 42% reduction in pigmentation intensity after 4 months and zero irritation and zero dropouts among participants. Unlike hydroquinone, cysteamine does not carry risks of ochronosis with long-term use, is not restricted in many markets, and does not require a prescription. It represents a clinically equivalent but safer and more accessible alternative.
Yes, and this is one of its most important uses. Melasma is a chronic, relapsing condition. Continuous use of Mela Bright [C+] as a maintenance treatment — even after visible pigmentation has resolved — helps sustain the regulation of overactive melanocytes and reduces the risk of recurrence, particularly during periods of higher UV exposure.
Some users experience very mild tingling or warmth on first applications, primarily due to the pH and Vitamin C content. This is not a sign of an allergic reaction and typically resolves within the first week of use. If redness, peeling or persistent discomfort occurs, reduce to once daily or every other day and build up gradually. Genuine intolerance to this formula is very uncommon.
Yes, and the combination is clinically endorsed. Apply Mela Bright [C+] daily for 2–3 weeks before a depigmenting procedure (laser, peel, cosmela) to pre-condition the skin and reduce rebound risk. After the procedure, pause the serum until acute inflammation has resolved — typically 2–3 days — then reintroduce. Continuous use supports the longevity of in-clinic results and helps prevent recurrence.